CoQ10 is found in especially high concentrations in your heart, liver, kidneys and pancreas. Mitochondria are the little powerhouses that make all the energy to keep your body functioning! You can obtain small amounts from certain types of foods—3 oz. It is not possible to get enough CoQ10 through your diet. The good news is that CoQ10 can be manufactured as a supplement by fermenting beets and sugar with special strains of yeast.
Many healthcare providers suggest individuals over the age of 50 take at least mg of CoQ10 supplement per day AND add an additional mg for every decade of life thereafter. Blood tests can be used to evaluate the levels of CoQ10 in your body. CoQ10 can help lower oxidative damage, promote exercise capacity and decrease fatigue.
Oxidative stress can induce cell damage. This can result in metabolic diseases like diabetes Abnormal mitochondrial function has also been linked to insulin resistance CoQ10 has been shown to improve insulin sensitivity and regulate blood sugar levels Supplementing with CoQ10 might also help increase CoQ10 concentrations in the blood by up to three times in people with diabetes who typically show low levels of this compound 37 , Also, one study had people with type 2 diabetes supplement with CoQ10 for 12 weeks.
Doing so significantly reduced fasting blood sugar levels and hemoglobin A1C, which is the average of blood sugar levels over the past two to three months Lastly, CoQ10 might help prevent diabetes by stimulating the breakdown of fats and reducing the accumulation of fat cells that could lead to obesity or type 2 diabetes Summary: Supplementing with CoQ10 can help increase insulin sensitivity and improve blood sugar levels.
Oxidative stress is known to cause cell damage and affect their function If your body is unable to effectively fight oxidative damage, the structure of your cells can become damaged, possibly increasing the risk of cancer 41 , CoQ10 may protect cells from oxidative stress and promote cellular energy production, promoting their health and survival 42 , Low levels of CoQ10 have been associated with up to a Summary: CoQ10 plays a critical role in the protection of cell DNA and cell survival, both of which are strongly linked to cancer prevention and recurrence.
Mitochondrial function tends to decrease with age. Unfortunately, the brain is very susceptible to oxidative damage due to its high fatty acid content and its high demand for oxygen. This oxidative damage enhances the production of harmful compounds that could affect memory, cognition and physical functions 48 , Summary: CoQ10 has been shown to protect brain cells from oxidative damage and reduce the action of harmful compounds that can lead to brain disease.
Of all your organs, your lungs have the most contact with oxygen. This makes them very susceptible to oxidative damage. Increased oxidative damage in the lungs and poor antioxidant protection, including low levels of CoQ10, can result in lung diseases like asthma and chronic obstructive pulmonary disease COPD Furthermore, it has been shown that people suffering from these conditions present lower levels of CoQ10 53 , A study demonstrated that supplementing with CoQ10 reduced inflammation in individuals who had asthma, as well as their need for steroid medications to treat it Another study showed improvements in exercise performance in those suffering from COPD.
This was observed through better tissue oxygenation and heart rate after supplementing with CoQ10 Summary: CoQ10 can reduce oxidative damage and inflammation that results in diseases of the lungs. If you want to buy a CoQ10 supplement containing the ubiquinol form, then there is an excellent selection on Amazon. The standard dose of CoQ10 ranges from 90 mg to mg per day.
Doses up to mg seem well tolerated, and several studies have used even higher doses without any serious side effects 59 , 60 , Because CoQ10 is a fat-soluble compound, its absorption is slow and limited.
However, taking CoQ10 supplements with food can help your body absorb it up to three times faster than taking it without food 2 , Additionally, some products offer a solubilized form of CoQ10, or a combination of CoQ10 and oils, to improve its absorption 63 , 64 , Your body does not store CoQ Therefore, its continued use is recommended to see its benefits 58 , Supplementing with CoQ10 appears to be well tolerated by humans and have low toxicity In fact, participants in some studies showed no major side effects taking daily doses of 1, mg for 16 months However, if side effects appear, it is recommended to divide the daily dose into two to three smaller doses.
Summary: Since CoQ10 is fat-soluble, it is recommended to take it with food or use products that combine it with oils to improve its absorption. Supplementing with CoQ10 appears to be well tolerated by individuals and has low toxicity. It appears that CoQ10 is similarly absorbed in capsule form or through foods Summary: CoQ10 is found in some foods, especially organ meats. These properties make it helpful in the preservation of cells and the prevention and treatment of some chronic diseases.
The amount of CoQ10 found in these dietary sources, however, isn't enough to significantly increase CoQ10 levels in your body. CoQ10 dietary supplements are available as capsules, chewable tablets, liquid syrups, wafers and by IV. CoQ10 might help prevent or treat certain heart conditions, as well as migraine headaches.
Research on CoQ10 use for specific conditions and activities shows:. CoQ10 supplements might be beneficial for treating conditions such as congestive heart failure and preventing migraines.
CoQ10 is considered safe, with few side effects. However, be sure to take this supplement under your doctor's supervision. CoQ10 supplements appear to be safe and to produce few side effects when taken as directed. The safety of use of CoQ10 during pregnancy and breast-feeding hasn't been established. Don't use CoQ10 if you're pregnant or breast-feeding without your doctor's approval. There is a problem with information submitted for this request. Sign up for free, and stay up-to-date on research advancements, health tips and current health topics, like COVID, plus expert advice on managing your health.
Error Email field is required. Error Include a valid email address. To provide you with the most relevant and helpful information and to understand which information is beneficial, we may combine your e-mail and website usage information with other information we have about you.
If we combine this information with your PHI, we will treat all of that information as PHI, and will only use or disclose that information as set forth in our notice of privacy practices. You may opt-out of e-mail communications at any time by clicking on the Unsubscribe link in the e-mail.
Our Housecall e-newsletter will keep you up-to-date on the latest health information. Mayo Clinic does not endorse companies or products.
0コメント